STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZC2HC1CZinc finger C2HC-type containing 1C. (456 aa)    
Predicted Functional Partners:
LEO1
Leo1, Paf1/RNA polymerase II complex component, homolog.
   
 
 0.837
RBM25
RNA binding motif protein 25.
   
 
 0.768
CDC5L
CDC5 cell division cycle 5-like.
   
 
 0.718
U2AF2
U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family.
    
 
 0.646
SF3B3
Splicing factor 3b, subunit 3, 130kDa.
    
 
 0.619
SF3B2
Splicing factor 3b, subunit 2, 145kDa.
   
 
 0.617
PRPF39
PRP39 pre-mRNA processing factor 39 homolog.
    
 
 0.616
SNRNP70
Small nuclear ribonucleoprotein U1 subunit 70.
   
 
 0.606
SNRNP35
Small nuclear ribonucleoprotein U11/U12 subunit 35.
   
 
 0.606
RNF20
E3 ubiquitin protein ligase; Belongs to the BRE1 family.
   
 0.579
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.