STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CYP46A1Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family. (500 aa)    
Predicted Functional Partners:
CYP7A1
Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.
  
 
 0.967
CH25H
Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family.
   
 0.964
CYP39A1
Cytochrome P450, family 39, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family.
  
 
 0.964
CYP27A1
Cytochrome P450, family 27, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family.
  
 
0.933
DHCR7
7-dehydrocholesterol reductase.
   
 0.892
DHCR24
24-dehydrocholesterol reductase.
   
 0.883
SOAT1
O-acyltransferase.
    
 0.859
SOAT2
O-acyltransferase.
    
 0.821
LIPA
Lipase; Belongs to the AB hydrolase superfamily. Lipase family.
  
 0.820
CYP7B1
Cytochrome P450, family 7, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family.
  
  
 0.754
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.