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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (570 aa)    
Predicted Functional Partners:
TBK1
TANK-binding kinase 1.
   
 0.999
MAVS
Mitochondrial antiviral signaling protein.
    
 0.999
IKBKE
Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon.
   
 0.999
TANK
TANK isoform 1.
    
 0.999
MAP3K14
Mitogen-activated protein kinase kinase kinase 14.
   
 0.998
BIRC2
Baculoviral IAP repeat containing 2.
   
 0.997
BIRC3
Baculoviral IAP repeat containing 3.
   
 0.997
LTBR
Lymphotoxin beta receptor (TNFR superfamily, member 3).
    
 0.996
TRADD
TNFRSF1A-associated via death domain.
    
 0.996
TNFRSF13C
TNF receptor superfamily member 13C.
   
 0.994
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.