STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OTUD7AOTU deubiquitinase 7A. (924 aa)    
Predicted Functional Partners:
MTMR10
Myotubularin related protein 10.
      
 0.763
UBXN7
UBX domain-containing protein 7.
   
 
 0.705
IER3IP1
Immediate early response 3 interacting protein 1.
      
 0.702
UBC
Polyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...]
   
  0.693
FAM72A
Uncharacterized protein.
      
 0.685
CASTOR2
GATS protein-like 2.
      
 0.675
ZUP1
Zinc finger with UFM1-specific peptidase domain.
      
 0.663
TRPM1
Transient receptor potential cation channel subfamily M member 1.
    
 
 0.631
WDR26
WD repeat domain 26.
   
  
 0.616
RPS27A
RPS27A isoform 1.
   
  0.616
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.