STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BUB1BBUB1B-PAK6 isoform 4. (1068 aa)    
Predicted Functional Partners:
ANAPC4
Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family.
    
 0.999
CDC23
Cell division cycle 23 homolog.
   
 0.999
BUB3
Budding uninhibited by benzimidazoles 3 homolog.
   
 0.999
NEK2
NIMA (Never in mitosis gene a)-related kinase 2.
   
 0.998
MAD2L1
MAD2 mitotic arrest deficient-like 1.
   
 0.998
BUB1
BUB1 isoform 1.
   
0.998
ANAPC7
Anaphase promoting complex subunit 7.
    
 0.997
CDC20
Cell division cycle 20 homolog.
   
 0.996
MAD1L1
MAD1 mitotic arrest deficient-like 1.
    
 0.995
CDC16
Cell division cycle 16 homolog.
   
 0.994
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.