STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TYRO3TYRO3 protein tyrosine kinase. (890 aa)    
Predicted Functional Partners:
FOLR1
Folate receptor alpha.
     
 0.631
PROS1
Protein S (Alpha).
     
 0.627
TAB1
TGF-beta activated kinase 1 (MAP3K7) binding protein 1.
  
 0.571
MIB2
Mindbomb homolog 2.
   
 0.541
TRADD
TNFRSF1A-associated via death domain.
   
 0.534
FADD
FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.
   
 0.531
TAB2
TGF-beta activated kinase 1 (MAP3K7) binding protein 2.
    
 0.531
TAB3
TGF-beta activated kinase 1 (MAP3K7) binding protein 3.
    
 0.531
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.530
ENSPTRP00000065244
annotation not available
   
 0.530
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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