B2M protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B2M	CD1D	ENSPTRP00000011997	ENSPTRP00000060660	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	Antigen-presenting glycoprotein CD1d; Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T- cells.	0.962
B2M	ENSPTRP00000066786	ENSPTRP00000011997	ENSPTRP00000066786	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	LOW QUALITY PROTEIN: HLA class I histocompatibility antigen, A-3 alpha chain.	0.962
B2M	HLA-A	ENSPTRP00000011997	ENSPTRP00000089515	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	Patr class I histocompatibility antigen, A-108 alpha chain; Involved in the presentation of foreign antigens to the immune system.	0.988
B2M	HLA-DQB1	ENSPTRP00000011997	ENSPTRP00000030768	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	HLA class II histocompatibility antigen, DQ beta 1 chain isoform X3.	0.912
B2M	PATR-B	ENSPTRP00000011997	ENSPTRP00000065181	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	Patr class I histocompatibility antigen, C alpha chain; Involved in the presentation of foreign antigens to the immune system.	0.965
B2M	PATR-DRA	ENSPTRP00000011997	ENSPTRP00000030766	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	MHC class II protein; Belongs to the MHC class II family.	0.916
B2M	PATR-E	ENSPTRP00000011997	ENSPTRP00000093472	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	Patr class I histocompatibility antigen, alpha chain E; Preferably binds to a peptide derived from the signal sequence of most HLA-A, -B, -C and -G molecules.	0.988
B2M	PATR-F	ENSPTRP00000011997	ENSPTRP00000054635	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	Patr class I histocompatibility antigen, CH28 alpha chain; Involved in the presentation of foreign antigens to the immune system.	0.973
B2M	PATR-G	ENSPTRP00000011997	ENSPTRP00000056399	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	Patr class I histocompatibility antigen, alpha chain G; Involved in the presentation of foreign antigens to the immune system.	0.969
B2M	RPA1	ENSPTRP00000011997	ENSPTRP00000014573	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.933
CD1D	B2M	ENSPTRP00000060660	ENSPTRP00000011997	Antigen-presenting glycoprotein CD1d; Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T- cells.	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	0.962
ENSPTRP00000066786	B2M	ENSPTRP00000066786	ENSPTRP00000011997	LOW QUALITY PROTEIN: HLA class I histocompatibility antigen, A-3 alpha chain.	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	0.962
ENSPTRP00000066786	HLA-A	ENSPTRP00000066786	ENSPTRP00000089515	LOW QUALITY PROTEIN: HLA class I histocompatibility antigen, A-3 alpha chain.	Patr class I histocompatibility antigen, A-108 alpha chain; Involved in the presentation of foreign antigens to the immune system.	0.656
ENSPTRP00000066786	HLA-DQB1	ENSPTRP00000066786	ENSPTRP00000030768	LOW QUALITY PROTEIN: HLA class I histocompatibility antigen, A-3 alpha chain.	HLA class II histocompatibility antigen, DQ beta 1 chain isoform X3.	0.407
ENSPTRP00000066786	PATR-B	ENSPTRP00000066786	ENSPTRP00000065181	LOW QUALITY PROTEIN: HLA class I histocompatibility antigen, A-3 alpha chain.	Patr class I histocompatibility antigen, C alpha chain; Involved in the presentation of foreign antigens to the immune system.	0.765
ENSPTRP00000066786	PATR-DRA	ENSPTRP00000066786	ENSPTRP00000030766	LOW QUALITY PROTEIN: HLA class I histocompatibility antigen, A-3 alpha chain.	MHC class II protein; Belongs to the MHC class II family.	0.546
ENSPTRP00000066786	PATR-E	ENSPTRP00000066786	ENSPTRP00000093472	LOW QUALITY PROTEIN: HLA class I histocompatibility antigen, A-3 alpha chain.	Patr class I histocompatibility antigen, alpha chain E; Preferably binds to a peptide derived from the signal sequence of most HLA-A, -B, -C and -G molecules.	0.661
ENSPTRP00000066786	PATR-F	ENSPTRP00000066786	ENSPTRP00000054635	LOW QUALITY PROTEIN: HLA class I histocompatibility antigen, A-3 alpha chain.	Patr class I histocompatibility antigen, CH28 alpha chain; Involved in the presentation of foreign antigens to the immune system.	0.650
ENSPTRP00000066786	PATR-G	ENSPTRP00000066786	ENSPTRP00000056399	LOW QUALITY PROTEIN: HLA class I histocompatibility antigen, A-3 alpha chain.	Patr class I histocompatibility antigen, alpha chain G; Involved in the presentation of foreign antigens to the immune system.	0.816
HLA-A	B2M	ENSPTRP00000089515	ENSPTRP00000011997	Patr class I histocompatibility antigen, A-108 alpha chain; Involved in the presentation of foreign antigens to the immune system.	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	0.988