STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HDCHistidine decarboxylase. (662 aa)    
Predicted Functional Partners:
CNDP2
CNDP dipeptidase 2 (Metallopeptidase M20 family).
   
 
 0.956
AOC1
Amine oxidase.
     
 0.953
HNMT
Histamine N-methyltransferase.
     
 0.950
HAL
Histidine ammonia-lyase; Belongs to the PAL/histidase family.
     
 0.922
CNDP1
Carnosine dipeptidase 1.
   
 
 0.922
CARNS1
Carnosine synthase 1.
     
 0.909
CPA3
CPA3 isoform 1.
   
  
 0.869
DPM2
Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family.
      
 0.865
MS4A2
Membrane spanning 4-domains A2.
   
  
 0.816
HRH1
Histamine H1 receptor; In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system.
      
 0.730
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.