STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GABPB1GA binding protein transcription factor subunit beta 1. (319 aa)    
Predicted Functional Partners:
GABPA
GA binding protein transcription factor, alpha subunit 60kDa.
   
 0.991
ENSPTRP00000076211
annotation not available
   
 0.991
TUBA1A
Detyrosinated tubulin alpha-1A chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity).
   
  0.833
TP63
Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.
    
  0.833
CTSB
CTSB isoform 10; Belongs to the peptidase C1 family.
    
   0.826
CASP2
Caspase 2, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
    
  0.818
CASP2-2
Caspase 2.
    
  0.818
TPD52L2
TPD52L2 isoform 8.
    
  0.795
ENSPTRP00000071983
annotation not available
   
  0.777
CK820_G0051601
TUBB3 isoform 13.
   
  0.777
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.