LEO1 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC73	CINP	ENSPTRP00000090347	ENSPTRP00000066729	Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog.	Cyclin dependent kinase 2 interacting protein.	0.888
CDC73	CTR9	ENSPTRP00000090347	ENSPTRP00000041382	Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog.	Ctr9, Paf1/RNA polymerase II complex component, homolog.	0.999
CDC73	ENSPTRP00000061528	ENSPTRP00000090347	ENSPTRP00000061528	Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog.	annotation not available	0.889
CDC73	IWS1	ENSPTRP00000090347	ENSPTRP00000021285	Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog.	Interacts with SUPT6H, CTD assembly factor 1.	0.716
CDC73	LEO1	ENSPTRP00000090347	ENSPTRP00000012100	Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog.	Leo1, Paf1/RNA polymerase II complex component, homolog.	0.998
CDC73	PAF1	ENSPTRP00000090347	ENSPTRP00000081951	Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog.	Paf1, RNA polymerase II associated factor, homolog.	0.999
CDC73	RTF1	ENSPTRP00000090347	ENSPTRP00000011849	Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog.	Rtf1, Paf1/RNA polymerase II complex component, homolog.	0.998
CDC73	SSRP1	ENSPTRP00000090347	ENSPTRP00000006311	Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.929
CDC73	SUPT16H	ENSPTRP00000090347	ENSPTRP00000010390	Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog.	SPT16 homolog, facilitates chromatin remodeling subunit.	0.889
CDC73	WDR61	ENSPTRP00000090347	ENSPTRP00000012547	Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog.	WD repeat domain 61.	0.999
CINP	CDC73	ENSPTRP00000066729	ENSPTRP00000090347	Cyclin dependent kinase 2 interacting protein.	Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog.	0.888
CINP	ENSPTRP00000061528	ENSPTRP00000066729	ENSPTRP00000061528	Cyclin dependent kinase 2 interacting protein.	annotation not available	0.785
CINP	IWS1	ENSPTRP00000066729	ENSPTRP00000021285	Cyclin dependent kinase 2 interacting protein.	Interacts with SUPT6H, CTD assembly factor 1.	0.803
CINP	LEO1	ENSPTRP00000066729	ENSPTRP00000012100	Cyclin dependent kinase 2 interacting protein.	Leo1, Paf1/RNA polymerase II complex component, homolog.	0.976
CINP	PAF1	ENSPTRP00000066729	ENSPTRP00000081951	Cyclin dependent kinase 2 interacting protein.	Paf1, RNA polymerase II associated factor, homolog.	0.902
CINP	RTF1	ENSPTRP00000066729	ENSPTRP00000011849	Cyclin dependent kinase 2 interacting protein.	Rtf1, Paf1/RNA polymerase II complex component, homolog.	0.858
CINP	SSRP1	ENSPTRP00000066729	ENSPTRP00000006311	Cyclin dependent kinase 2 interacting protein.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.879
CINP	SUPT16H	ENSPTRP00000066729	ENSPTRP00000010390	Cyclin dependent kinase 2 interacting protein.	SPT16 homolog, facilitates chromatin remodeling subunit.	0.785
CINP	WDR61	ENSPTRP00000066729	ENSPTRP00000012547	Cyclin dependent kinase 2 interacting protein.	WD repeat domain 61.	0.576
CTR9	CDC73	ENSPTRP00000041382	ENSPTRP00000090347	Ctr9, Paf1/RNA polymerase II complex component, homolog.	Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog.	0.999