| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ASF1A | ASF1B | ENSPTRP00000031677 | ENSPTRP00000084870 | Anti-silencing function 1A histone chaperone. | Anti-silencing function 1B histone chaperone. | 0.928 |
| ASF1A | ATR | ENSPTRP00000031677 | ENSPTRP00000051017 | Anti-silencing function 1A histone chaperone. | Ataxia telangiectasia and Rad3 related; Belongs to the PI3/PI4-kinase family. | 0.577 |
| ASF1A | BLM | ENSPTRP00000031677 | ENSPTRP00000012754 | Anti-silencing function 1A histone chaperone. | BLM isoform 1. | 0.615 |
| ASF1A | PIF1 | ENSPTRP00000031677 | ENSPTRP00000012249 | Anti-silencing function 1A histone chaperone. | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] | 0.854 |
| ASF1A | RAD51 | ENSPTRP00000031677 | ENSPTRP00000068995 | Anti-silencing function 1A histone chaperone. | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] | 0.607 |
| ASF1A | WRN | ENSPTRP00000031677 | ENSPTRP00000091996 | Anti-silencing function 1A histone chaperone. | WRN RecQ like helicase. | 0.636 |
| ASF1B | ASF1A | ENSPTRP00000084870 | ENSPTRP00000031677 | Anti-silencing function 1B histone chaperone. | Anti-silencing function 1A histone chaperone. | 0.928 |
| ASF1B | ATR | ENSPTRP00000084870 | ENSPTRP00000051017 | Anti-silencing function 1B histone chaperone. | Ataxia telangiectasia and Rad3 related; Belongs to the PI3/PI4-kinase family. | 0.577 |
| ASF1B | BLM | ENSPTRP00000084870 | ENSPTRP00000012754 | Anti-silencing function 1B histone chaperone. | BLM isoform 1. | 0.635 |
| ASF1B | PIF1 | ENSPTRP00000084870 | ENSPTRP00000012249 | Anti-silencing function 1B histone chaperone. | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] | 0.854 |
| ASF1B | RAD51 | ENSPTRP00000084870 | ENSPTRP00000068995 | Anti-silencing function 1B histone chaperone. | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] | 0.627 |
| ASF1B | WRN | ENSPTRP00000084870 | ENSPTRP00000091996 | Anti-silencing function 1B histone chaperone. | WRN RecQ like helicase. | 0.636 |
| ATR | ASF1A | ENSPTRP00000051017 | ENSPTRP00000031677 | Ataxia telangiectasia and Rad3 related; Belongs to the PI3/PI4-kinase family. | Anti-silencing function 1A histone chaperone. | 0.577 |
| ATR | ASF1B | ENSPTRP00000051017 | ENSPTRP00000084870 | Ataxia telangiectasia and Rad3 related; Belongs to the PI3/PI4-kinase family. | Anti-silencing function 1B histone chaperone. | 0.577 |
| ATR | BLM | ENSPTRP00000051017 | ENSPTRP00000012754 | Ataxia telangiectasia and Rad3 related; Belongs to the PI3/PI4-kinase family. | BLM isoform 1. | 0.923 |
| ATR | DNA2 | ENSPTRP00000051017 | ENSPTRP00000063857 | Ataxia telangiectasia and Rad3 related; Belongs to the PI3/PI4-kinase family. | DNA2 isoform 3. | 0.932 |
| ATR | FBH1 | ENSPTRP00000051017 | ENSPTRP00000003825 | Ataxia telangiectasia and Rad3 related; Belongs to the PI3/PI4-kinase family. | FBXO18 isoform 3. | 0.794 |
| ATR | MUS81 | ENSPTRP00000051017 | ENSPTRP00000006717 | Ataxia telangiectasia and Rad3 related; Belongs to the PI3/PI4-kinase family. | MUS81 structure-specific endonuclease subunit. | 0.826 |
| ATR | PIF1 | ENSPTRP00000051017 | ENSPTRP00000012249 | Ataxia telangiectasia and Rad3 related; Belongs to the PI3/PI4-kinase family. | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] | 0.792 |
| ATR | RAD51 | ENSPTRP00000051017 | ENSPTRP00000068995 | Ataxia telangiectasia and Rad3 related; Belongs to the PI3/PI4-kinase family. | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] | 0.922 |
