STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRRC49Leucine rich repeat containing 49. (691 aa)    
Predicted Functional Partners:
TTLL1
Tubulin tyrosine ligase-like family, member 1.
   
 0.983
TPGS1
Tubulin polyglutamylase complex subunit 1.
    
 0.982
NICN1
NICN1 isoform 2.
   
 0.978
TPGS2
Tubulin polyglutamylase complex subunit 2.
    
 0.969
C11H11orf49
Chromosome 11 open reading frame 49.
    
 
 0.860
TBC1D19
TBC1 domain family, member 19.
   
   0.738
KIAA1841
KIAA1841 isoform 3.
    
   0.725
EIF3F
Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]
    
  0.723
ENSPTRP00000066251
annotation not available
   
 0.686
ENSPTRP00000087891
annotation not available
    
  0.637
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.