STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIN3BSIN3 transcription regulator family member B. (1159 aa)    
Predicted Functional Partners:
SAP30
Sin3A-associated protein, 30kDa.
    
 0.985
SUDS3
SDS3 homolog, SIN3A corepressor complex component.
   
 0.985
HDAC2
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
   
 0.976
HDAC1
Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
   
 0.975
SIN3A
SIN3 transcription regulator family member A.
  
 
0.968
RBBP7
RBBP7 isoform 5.
   
 0.961
PHF12
PHD finger protein 12.
   
 0.955
LOC748850
HDAC2 isoform 9.
   
 0.954
SAP130
Sin3A-associated protein, 130kDa.
   
 0.926
ARID4B
AT rich interactive domain 4B (RBP1-like).
   
 0.922
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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