STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CK820_G0036696PSTPIP1 isoform 2. (356 aa)    
Predicted Functional Partners:
ITSN2
ITSN2 isoform 1.
   
 0.964
PTPN12
Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades.
   
 
 0.939
PTPN22
Protein tyrosine phosphatase, non-receptor type 22 (Lymphoid).
   
 
 0.906
MEFV
MEFV isoform 5.
   
 0.859
MEFV-2
MEFV isoform 4.
   
 0.859
ITSN1
ITSN1 isoform 4.
   
 0.840
ITSN1-2
ITSN1 isoform 7.
   
 0.840
WAS
WAS isoform 1.
   
 0.836
WAS-2
WASP actin nucleation promoting factor.
   
 0.836
CD2
CD2 isoform 1.
   
 
 0.778
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.