STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CTSHCTSH isoform 11; Belongs to the peptidase C1 family. (335 aa)    
Predicted Functional Partners:
BID
BH3-interacting domain death agonist; Counters the protective effect of Bcl-2.
   
 
 0.907
BCL2
BCL2 apoptosis regulator.
   
 
 0.904
BCL2L1
BCL2L1 isoform 6.
     
 0.901
CSTA
Cystatin A (Stefin A); Belongs to the cystatin family.
   
 0.842
CRISP1
Cysteine rich secretory protein 1; Belongs to the CRISP family.
   
 
 0.770
ANKRD34C
Ankyrin repeat domain 34C.
    
 
 0.766
CLN5
CLN5 intracellular trafficking protein.
      
 0.737
MYH9
Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 0.727
HIST1H1C
HIST1H1C isoform 1.
    
 
 0.710
CTSD
T0155181 isoform 2; Belongs to the peptidase A1 family.
   
 0.671
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.