CIB1 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGEF1	CHD6	ENSPTRP00000018955	ENSPTRP00000065368	Rho guanine nucleotide exchange factor 1.	Chromodomain helicase DNA binding protein 6.	0.759
ARHGEF1	CIB1	ENSPTRP00000018955	ENSPTRP00000012735	Rho guanine nucleotide exchange factor 1.	Calcium and integrin binding 1.	0.840
ARHGEF1	GPR37	ENSPTRP00000018955	ENSPTRP00000033642	Rho guanine nucleotide exchange factor 1.	G protein-coupled receptor 37.	0.779
ARHGEF1	GRIN3A	ENSPTRP00000018955	ENSPTRP00000039833	Rho guanine nucleotide exchange factor 1.	GRIN3A isoform 1.	0.761
ARHGEF1	MCM7	ENSPTRP00000018955	ENSPTRP00000033323	Rho guanine nucleotide exchange factor 1.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.716
ARHGEF1	NIN	ENSPTRP00000018955	ENSPTRP00000082651	Rho guanine nucleotide exchange factor 1.	NIN isoform 1.	0.788
ARHGEF1	PTPRG	ENSPTRP00000018955	ENSPTRP00000026022	Rho guanine nucleotide exchange factor 1.	Protein tyrosine phosphatase, receptor type, G.	0.755
ARHGEF1	SPICE1	ENSPTRP00000018955	ENSPTRP00000026268	Rho guanine nucleotide exchange factor 1.	Spindle and centriole associated protein 1.	0.799
ARHGEF1	THOP1	ENSPTRP00000018955	ENSPTRP00000057817	Rho guanine nucleotide exchange factor 1.	Thimet oligopeptidase 1.	0.756
CHD6	ARHGEF1	ENSPTRP00000065368	ENSPTRP00000018955	Chromodomain helicase DNA binding protein 6.	Rho guanine nucleotide exchange factor 1.	0.759
CHD6	CIB1	ENSPTRP00000065368	ENSPTRP00000012735	Chromodomain helicase DNA binding protein 6.	Calcium and integrin binding 1.	0.830
CHD6	GPR37	ENSPTRP00000065368	ENSPTRP00000033642	Chromodomain helicase DNA binding protein 6.	G protein-coupled receptor 37.	0.821
CHD6	GRIN3A	ENSPTRP00000065368	ENSPTRP00000039833	Chromodomain helicase DNA binding protein 6.	GRIN3A isoform 1.	0.822
CHD6	MCM7	ENSPTRP00000065368	ENSPTRP00000033323	Chromodomain helicase DNA binding protein 6.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.828
CHD6	NIN	ENSPTRP00000065368	ENSPTRP00000082651	Chromodomain helicase DNA binding protein 6.	NIN isoform 1.	0.694
CHD6	PTPRG	ENSPTRP00000065368	ENSPTRP00000026022	Chromodomain helicase DNA binding protein 6.	Protein tyrosine phosphatase, receptor type, G.	0.759
CHD6	SPICE1	ENSPTRP00000065368	ENSPTRP00000026268	Chromodomain helicase DNA binding protein 6.	Spindle and centriole associated protein 1.	0.755
CHD6	THOP1	ENSPTRP00000065368	ENSPTRP00000057817	Chromodomain helicase DNA binding protein 6.	Thimet oligopeptidase 1.	0.749
CIB1	ARHGEF1	ENSPTRP00000012735	ENSPTRP00000018955	Calcium and integrin binding 1.	Rho guanine nucleotide exchange factor 1.	0.840
CIB1	CHD6	ENSPTRP00000012735	ENSPTRP00000065368	Calcium and integrin binding 1.	Chromodomain helicase DNA binding protein 6.	0.830