STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FURINFurin (Paired basic amino acid cleaving enzyme); Belongs to the peptidase S8 family. (794 aa)    
Predicted Functional Partners:
TMPRSS2
Transmembrane serine protease 2; Belongs to the peptidase S1 family.
  
 
 0.863
ADAM17
ADAM17 isoform 3.
     
 0.855
ACE2
Angiotensin-converting enzyme.
      
 0.854
MMP11
Matrix metallopeptidase 11 (Stromelysin 3).
    
 0.800
MMP14
Matrix metallopeptidase 14.
    
 0.798
CK820_G0044543
COL23A1 isoform 1.
    
 0.774
TGFB1
Transforming growth factor beta; Belongs to the TGF-beta family.
   
 0.766
GP2
Glycoprotein 2.
   
 0.763
CTSL
CTSL isoform 2; Belongs to the peptidase C1 family.
  
 
 0.757
LOC473484
Cathepsin L1.
  
 
 0.757
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.