node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CUL5 | TNP2 | ENSPTRP00000007307 | ENSPTRP00000013257 | CUL5 isoform 1; Belongs to the cullin family. | Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. | 0.607 |
DMRT1 | MSH4 | ENSPTRP00000035458 | ENSPTRP00000084312 | Doublesex and mab-3 related transcription factor 1. | MSH4 isoform 1. | 0.765 |
DMRT1 | PRM1 | ENSPTRP00000035458 | ENSPTRP00000013259 | Doublesex and mab-3 related transcription factor 1. | Protamine-2; Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex. | 0.455 |
DMRT1 | TNP1 | ENSPTRP00000035458 | ENSPTRP00000022059 | Doublesex and mab-3 related transcription factor 1. | Spermatid nuclear transition protein 1. | 0.784 |
DMRT1 | TNP2 | ENSPTRP00000035458 | ENSPTRP00000013257 | Doublesex and mab-3 related transcription factor 1. | Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. | 0.733 |
LATS2 | TNP2 | ENSPTRP00000009705 | ENSPTRP00000013257 | Non-specific serine/threonine protein kinase. | Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. | 0.631 |
MSH4 | DMRT1 | ENSPTRP00000084312 | ENSPTRP00000035458 | MSH4 isoform 1. | Doublesex and mab-3 related transcription factor 1. | 0.765 |
MSH4 | TNP1 | ENSPTRP00000084312 | ENSPTRP00000022059 | MSH4 isoform 1. | Spermatid nuclear transition protein 1. | 0.711 |
MSH4 | TNP2 | ENSPTRP00000084312 | ENSPTRP00000013257 | MSH4 isoform 1. | Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. | 0.805 |
OR5AN1 | PINLYP | ENSPTRP00000050771 | ENSPTRP00000085138 | Olfactory receptor. | Phospholipase A2 inhibitor and LY6/PLAUR domain containing. | 0.793 |
OR5AN1 | PLAUR | ENSPTRP00000050771 | ENSPTRP00000054428 | Olfactory receptor. | Urokinase plasminogen activator surface receptor; Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form (By similarity). | 0.723 |
OR5AN1 | TNP2 | ENSPTRP00000050771 | ENSPTRP00000013257 | Olfactory receptor. | Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. | 0.686 |
PINLYP | OR5AN1 | ENSPTRP00000085138 | ENSPTRP00000050771 | Phospholipase A2 inhibitor and LY6/PLAUR domain containing. | Olfactory receptor. | 0.793 |
PINLYP | PLAUR | ENSPTRP00000085138 | ENSPTRP00000054428 | Phospholipase A2 inhibitor and LY6/PLAUR domain containing. | Urokinase plasminogen activator surface receptor; Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form (By similarity). | 0.584 |
PINLYP | TNP2 | ENSPTRP00000085138 | ENSPTRP00000013257 | Phospholipase A2 inhibitor and LY6/PLAUR domain containing. | Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. | 0.763 |
PLAUR | OR5AN1 | ENSPTRP00000054428 | ENSPTRP00000050771 | Urokinase plasminogen activator surface receptor; Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form (By similarity). | Olfactory receptor. | 0.723 |
PLAUR | PINLYP | ENSPTRP00000054428 | ENSPTRP00000085138 | Urokinase plasminogen activator surface receptor; Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form (By similarity). | Phospholipase A2 inhibitor and LY6/PLAUR domain containing. | 0.584 |
PLAUR | TNP2 | ENSPTRP00000054428 | ENSPTRP00000013257 | Urokinase plasminogen activator surface receptor; Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form (By similarity). | Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. | 0.610 |
PRM1 | DMRT1 | ENSPTRP00000013259 | ENSPTRP00000035458 | Protamine-2; Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex. | Doublesex and mab-3 related transcription factor 1. | 0.455 |
PRM1 | TNP1 | ENSPTRP00000013259 | ENSPTRP00000022059 | Protamine-2; Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex. | Spermatid nuclear transition protein 1. | 0.877 |