STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDILTPDILT isoform 1. (584 aa)    
Predicted Functional Partners:
GAK
Cyclin G associated kinase.
    
 0.751
CALR3
Calreticulin.
   
 0.722
CLGN
CLGN isoform 1.
   
 0.634
PRDX5
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.628
MSRA
Methionine sulfoxide reductase A.
   
 0.588
PDIA5
Protein disulfide isomerase family A member 5.
      
 0.578
TMX1
Thioredoxin-related transmembrane protein 1.
      
 0.573
AGR3
Anterior gradient 3, protein disulphide isomerase family member.
      
 0.572
CALR
Calreticulin.
   
 0.547
TXNDC12
Thioredoxin domain containing 12 (Endoplasmic reticulum).
    
 0.544
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.