SCNN1G protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARG2	EPB41L4B	ENSPTRP00000010966	ENSPTRP00000036284	Arginase.	EPB41L4B isoform 2.	0.514
ARG2	ESR2	ENSPTRP00000010966	ENSPTRP00000010911	Arginase.	Estrogen receptor 2.	0.661
ARG2	SCNN1G	ENSPTRP00000010966	ENSPTRP00000013456	Arginase.	Amiloride-sensitive sodium channel subunit gamma; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.	0.716
ARG2	TUBB1	ENSPTRP00000010966	ENSPTRP00000023535	Arginase.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.733
EPB41L4B	ARG2	ENSPTRP00000036284	ENSPTRP00000010966	EPB41L4B isoform 2.	Arginase.	0.514
EPB41L4B	ESR2	ENSPTRP00000036284	ENSPTRP00000010911	EPB41L4B isoform 2.	Estrogen receptor 2.	0.770
EPB41L4B	SCNN1G	ENSPTRP00000036284	ENSPTRP00000013456	EPB41L4B isoform 2.	Amiloride-sensitive sodium channel subunit gamma; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.	0.871
EPB41L4B	TUBB1	ENSPTRP00000036284	ENSPTRP00000023535	EPB41L4B isoform 2.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.880
ESR2	ARG2	ENSPTRP00000010911	ENSPTRP00000010966	Estrogen receptor 2.	Arginase.	0.661
ESR2	EPB41L4B	ENSPTRP00000010911	ENSPTRP00000036284	Estrogen receptor 2.	EPB41L4B isoform 2.	0.770
ESR2	SCNN1G	ENSPTRP00000010911	ENSPTRP00000013456	Estrogen receptor 2.	Amiloride-sensitive sodium channel subunit gamma; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.	0.749
ESR2	TUBB1	ENSPTRP00000010911	ENSPTRP00000023535	Estrogen receptor 2.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.759
NEDD4	NEDD4L	ENSPTRP00000085467	ENSPTRP00000062932	NEDD4 E3 ubiquitin protein ligase.	NEDD4L isoform 6.	0.965
NEDD4	SCNN1A	ENSPTRP00000085467	ENSPTRP00000064198	NEDD4 E3 ubiquitin protein ligase.	Amiloride-sensitive sodium channel subunit alpha; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and eccrine sweat glands. Also plays a role in taste perception.	0.961
NEDD4	SCNN1B	ENSPTRP00000085467	ENSPTRP00000013457	NEDD4 E3 ubiquitin protein ligase.	Amiloride-sensitive sodium channel subunit beta; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception; Belongs to the amiloride-sensit [...]	0.966
NEDD4	SCNN1D	ENSPTRP00000085467	ENSPTRP00000054494	NEDD4 E3 ubiquitin protein ligase.	Amiloride-sensitive sodium channel subunit delta; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.	0.831
NEDD4	SCNN1G	ENSPTRP00000085467	ENSPTRP00000013456	NEDD4 E3 ubiquitin protein ligase.	Amiloride-sensitive sodium channel subunit gamma; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.	0.929
NEDD4	SGK1	ENSPTRP00000085467	ENSPTRP00000085488	NEDD4 E3 ubiquitin protein ligase.	Non-specific serine/threonine protein kinase.	0.831
NEDD4L	NEDD4	ENSPTRP00000062932	ENSPTRP00000085467	NEDD4L isoform 6.	NEDD4 E3 ubiquitin protein ligase.	0.965
NEDD4L	SCNN1A	ENSPTRP00000062932	ENSPTRP00000064198	NEDD4L isoform 6.	Amiloride-sensitive sodium channel subunit alpha; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and eccrine sweat glands. Also plays a role in taste perception.	0.996