STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERN2ERN2 isoform 1. (926 aa)    
Predicted Functional Partners:
HSPA5
Heat shock 70kDa protein 5 (Glucose-regulated protein, 78kDa); Belongs to the heat shock protein 70 family.
    
 0.825
UBFD1
UBFD1 isoform 1.
 
  
 0.815
LOC100609513
78 kDa glucose-regulated protein pseudogene.
    
 0.798
DCTN5
Dynactin subunit 5.
      
 0.727
XBP1
XBP1 isoform 4.
    
 0.703
EARS2
EARS2 isoform 2; Belongs to the class-I aminoacyl-tRNA synthetase family.
    
 
 0.698
ANKRD45
Ankyrin repeat domain 45.
    
 0.695
NDUFAB1
Acyl carrier protein, mitochondrial; Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity). Accessory and non-catalytic subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain (By similarity).
      
 0.654
TRAF2
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.642
ATF6
Activating transcription factor 6.
    
 
 0.635
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.