| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMFR | DERL1 | ENSPTRP00000072262 | ENSPTRP00000035139 | Autocrine motility factor receptor. | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | 0.989 |
| AMFR | DERL2 | ENSPTRP00000072262 | ENSPTRP00000077709 | Autocrine motility factor receptor. | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | 0.967 |
| AMFR | INSIG1 | ENSPTRP00000072262 | ENSPTRP00000034091 | Autocrine motility factor receptor. | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. | 0.965 |
| AMFR | KXD1 | ENSPTRP00000072262 | ENSPTRP00000060271 | Autocrine motility factor receptor. | UBA52 isoform 10. | 0.980 |
| AMFR | RPS27A | ENSPTRP00000072262 | ENSPTRP00000020489 | Autocrine motility factor receptor. | RPS27A isoform 1. | 0.983 |
| AMFR | SEL1L | ENSPTRP00000072262 | ENSPTRP00000011221 | Autocrine motility factor receptor. | SEL1L adaptor subunit of ERAD E3 ubiquitin ligase. | 0.968 |
| AMFR | UBC | ENSPTRP00000072262 | ENSPTRP00000050925 | Autocrine motility factor receptor. | Polyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] | 0.994 |
| AMFR | UBE2G2 | ENSPTRP00000072262 | ENSPTRP00000024077 | Autocrine motility factor receptor. | Ubiquitin conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family. | 0.971 |
| AMFR | UBXN1 | ENSPTRP00000072262 | ENSPTRP00000006496 | Autocrine motility factor receptor. | UBX domain protein 1. | 0.974 |
| AMFR | VCP | ENSPTRP00000072262 | ENSPTRP00000035748 | Autocrine motility factor receptor. | Valosin containing protein; Belongs to the AAA ATPase family. | 0.987 |
| DERL1 | AMFR | ENSPTRP00000035139 | ENSPTRP00000072262 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | Autocrine motility factor receptor. | 0.989 |
| DERL1 | DERL2 | ENSPTRP00000035139 | ENSPTRP00000077709 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | 0.995 |
| DERL1 | KXD1 | ENSPTRP00000035139 | ENSPTRP00000060271 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | UBA52 isoform 10. | 0.489 |
| DERL1 | RPS27A | ENSPTRP00000035139 | ENSPTRP00000020489 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | RPS27A isoform 1. | 0.622 |
| DERL1 | SEL1L | ENSPTRP00000035139 | ENSPTRP00000011221 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | SEL1L adaptor subunit of ERAD E3 ubiquitin ligase. | 0.987 |
| DERL1 | UBC | ENSPTRP00000035139 | ENSPTRP00000050925 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | Polyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] | 0.643 |
| DERL1 | UBXN1 | ENSPTRP00000035139 | ENSPTRP00000006496 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | UBX domain protein 1. | 0.955 |
| DERL1 | VCP | ENSPTRP00000035139 | ENSPTRP00000035748 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | Valosin containing protein; Belongs to the AAA ATPase family. | 0.994 |
| DERL2 | AMFR | ENSPTRP00000077709 | ENSPTRP00000072262 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | Autocrine motility factor receptor. | 0.967 |
| DERL2 | DERL1 | ENSPTRP00000077709 | ENSPTRP00000035139 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | 0.995 |
