AMFR protein (Pan troglodytes) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

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[Homology]

Score

AMFR

Autocrine motility factor receptor. (643 aa)

Predicted Functional Partners:

UBE2G2

0.998

VCP

0.989

UBC

0.989

DERL1

0.988

INSIG1

0.979

DERL2

0.947

FAF2

0.937

NGLY1

0.932

ENSPTRP00000060412

0.928

ERLIN2

0.921

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMFR	DERL1	ENSPTRP00000072262	ENSPTRP00000035139	Autocrine motility factor receptor.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.988
AMFR	DERL2	ENSPTRP00000072262	ENSPTRP00000077709	Autocrine motility factor receptor.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.947
AMFR	ENSPTRP00000060412	ENSPTRP00000072262	ENSPTRP00000060412	Autocrine motility factor receptor.	annotation not available	0.928
AMFR	ERLIN2	ENSPTRP00000072262	ENSPTRP00000034509	Autocrine motility factor receptor.	ER lipid raft associated 2.	0.921
AMFR	FAF2	ENSPTRP00000072262	ENSPTRP00000072174	Autocrine motility factor receptor.	Fas associated factor family member 2.	0.937
AMFR	INSIG1	ENSPTRP00000072262	ENSPTRP00000034091	Autocrine motility factor receptor.	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	0.979
AMFR	NGLY1	ENSPTRP00000072262	ENSPTRP00000025357	Autocrine motility factor receptor.	NGLY1 isoform 3.	0.932
AMFR	UBC	ENSPTRP00000072262	ENSPTRP00000050925	Autocrine motility factor receptor.	Polyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...]	0.989
AMFR	UBE2G2	ENSPTRP00000072262	ENSPTRP00000024077	Autocrine motility factor receptor.	Ubiquitin conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family.	0.998
AMFR	VCP	ENSPTRP00000072262	ENSPTRP00000035748	Autocrine motility factor receptor.	Valosin containing protein; Belongs to the AAA ATPase family.	0.989
DERL1	AMFR	ENSPTRP00000035139	ENSPTRP00000072262	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Autocrine motility factor receptor.	0.988
DERL1	DERL2	ENSPTRP00000035139	ENSPTRP00000077709	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.961
DERL1	ENSPTRP00000060412	ENSPTRP00000035139	ENSPTRP00000060412	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	annotation not available	0.515
DERL1	ERLIN2	ENSPTRP00000035139	ENSPTRP00000034509	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	ER lipid raft associated 2.	0.587
DERL1	FAF2	ENSPTRP00000035139	ENSPTRP00000072174	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Fas associated factor family member 2.	0.833
DERL1	NGLY1	ENSPTRP00000035139	ENSPTRP00000025357	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	NGLY1 isoform 3.	0.890
DERL1	UBC	ENSPTRP00000035139	ENSPTRP00000050925	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Polyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...]	0.611
DERL1	VCP	ENSPTRP00000035139	ENSPTRP00000035748	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Valosin containing protein; Belongs to the AAA ATPase family.	0.999
DERL2	AMFR	ENSPTRP00000077709	ENSPTRP00000072262	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Autocrine motility factor receptor.	0.947
DERL2	DERL1	ENSPTRP00000077709	ENSPTRP00000035139	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.961