GOT2 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CS	FH	ENSPTRP00000008664	ENSPTRP00000003656	Citrate synthase, mitochondrial isoform X1.	Fumarate hydratase.	0.971
CS	GOT1	ENSPTRP00000008664	ENSPTRP00000004968	Citrate synthase, mitochondrial isoform X1.	Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...]	0.887
CS	GOT1L1	ENSPTRP00000008664	ENSPTRP00000093290	Citrate synthase, mitochondrial isoform X1.	GOT1L1 isoform 1.	0.878
CS	GOT2	ENSPTRP00000008664	ENSPTRP00000013976	Citrate synthase, mitochondrial isoform X1.	Aspartate aminotransferase.	0.964
CS	MDH1	ENSPTRP00000008664	ENSPTRP00000088176	Citrate synthase, mitochondrial isoform X1.	Malate dehydrogenase.	0.974
CS	MDH2	ENSPTRP00000008664	ENSPTRP00000033039	Citrate synthase, mitochondrial isoform X1.	Malate dehydrogenase.	0.996
FH	CS	ENSPTRP00000003656	ENSPTRP00000008664	Fumarate hydratase.	Citrate synthase, mitochondrial isoform X1.	0.971
FH	GOT1	ENSPTRP00000003656	ENSPTRP00000004968	Fumarate hydratase.	Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...]	0.959
FH	GOT1L1	ENSPTRP00000003656	ENSPTRP00000093290	Fumarate hydratase.	GOT1L1 isoform 1.	0.951
FH	GOT2	ENSPTRP00000003656	ENSPTRP00000013976	Fumarate hydratase.	Aspartate aminotransferase.	0.974
FH	GPT	ENSPTRP00000003656	ENSPTRP00000039118	Fumarate hydratase.	Glutamic--pyruvic transaminase.	0.914
FH	GPT2	ENSPTRP00000003656	ENSPTRP00000013801	Fumarate hydratase.	Glutamic pyruvate transaminase (Alanine aminotransferase) 2.	0.914
FH	KYAT3	ENSPTRP00000003656	ENSPTRP00000001612	Fumarate hydratase.	Cysteine conjugate-beta lyase 2.	0.543
FH	MDH1	ENSPTRP00000003656	ENSPTRP00000088176	Fumarate hydratase.	Malate dehydrogenase.	0.983
FH	MDH2	ENSPTRP00000003656	ENSPTRP00000033039	Fumarate hydratase.	Malate dehydrogenase.	0.998
FH	TAT	ENSPTRP00000003656	ENSPTRP00000014220	Fumarate hydratase.	Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.	0.534
GOT1	CS	ENSPTRP00000004968	ENSPTRP00000008664	Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...]	Citrate synthase, mitochondrial isoform X1.	0.887
GOT1	FH	ENSPTRP00000004968	ENSPTRP00000003656	Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...]	Fumarate hydratase.	0.959
GOT1	GOT1L1	ENSPTRP00000004968	ENSPTRP00000093290	Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...]	GOT1L1 isoform 1.	0.922
GOT1	GOT2	ENSPTRP00000004968	ENSPTRP00000013976	Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...]	Aspartate aminotransferase.	0.981