STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDH5CDH5 isoform 1; Cadherins are calcium-dependent cell adhesion proteins. (784 aa)    
Predicted Functional Partners:
CTNNB1
Catenin (Cadherin-associated protein), beta 1, 88kDa.
    
 0.998
CTNND1
CTNND1 isoform 23.
    
 0.998
PECAM1
Platelet/endothelial cell adhesion molecule.
   
 0.995
KDR
Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
 0.994
CTNNA1
CTNNA1 isoform 21.
    
 0.984
CDH1
CDH1 isoform 1; Cadherins are calcium-dependent cell adhesion proteins.
     
0.931
JUP
Junction plakoglobin.
    
 0.918
CDH2
Cadherin 2, type 1, N-cadherin (Neuronal); Cadherins are calcium-dependent cell adhesion proteins.
     
0.871
FLT4
Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
 
 0.870
TJP1
Tight junction protein 1; Belongs to the MAGUK family.
   
 0.854
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.