| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APOA1 | APOC1 | ENSPTRP00000007404 | ENSPTRP00000070626 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility (By similarity). | Cholesteryl ester transfer inhibitor protein; Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor. Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL. Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP). Binds free fatty acids and reduces their intracellular esterification. [...] | 0.923 |
| APOA1 | LCAT | ENSPTRP00000007404 | ENSPTRP00000014085 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility (By similarity). | Lecithin-cholesterol acyltransferase. | 0.963 |
| APOC1 | APOA1 | ENSPTRP00000070626 | ENSPTRP00000007404 | Cholesteryl ester transfer inhibitor protein; Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor. Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL. Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP). Binds free fatty acids and reduces their intracellular esterification. [...] | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility (By similarity). | 0.923 |
| APOC1 | LCAT | ENSPTRP00000070626 | ENSPTRP00000014085 | Cholesteryl ester transfer inhibitor protein; Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor. Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL. Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP). Binds free fatty acids and reduces their intracellular esterification. [...] | Lecithin-cholesterol acyltransferase. | 0.945 |
| CEPT1 | CHPT1 | ENSPTRP00000092990 | ENSPTRP00000009103 | Choline/ethanolamine phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Choline phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.901 |
| CEPT1 | LCAT | ENSPTRP00000092990 | ENSPTRP00000014085 | Choline/ethanolamine phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Lecithin-cholesterol acyltransferase. | 0.914 |
| CEPT1 | PEMT | ENSPTRP00000092990 | ENSPTRP00000015059 | Choline/ethanolamine phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Phosphatidylethanolamine N-methyltransferase; Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC); Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family. | 0.979 |
| CEPT1 | PLB1 | ENSPTRP00000092990 | ENSPTRP00000020244 | Choline/ethanolamine phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | PLB1 isoform 2. | 0.700 |
| CEPT1 | PLD1 | ENSPTRP00000092990 | ENSPTRP00000042550 | Choline/ethanolamine phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Phospholipase. | 0.940 |
| CEPT1 | PLD2 | ENSPTRP00000092990 | ENSPTRP00000014697 | Choline/ethanolamine phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Phospholipase. | 0.940 |
| CHPT1 | CEPT1 | ENSPTRP00000009103 | ENSPTRP00000092990 | Choline phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Choline/ethanolamine phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.901 |
| CHPT1 | LCAT | ENSPTRP00000009103 | ENSPTRP00000014085 | Choline phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Lecithin-cholesterol acyltransferase. | 0.923 |
| CHPT1 | PEMT | ENSPTRP00000009103 | ENSPTRP00000015059 | Choline phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Phosphatidylethanolamine N-methyltransferase; Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC); Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family. | 0.962 |
| CHPT1 | PLB1 | ENSPTRP00000009103 | ENSPTRP00000020244 | Choline phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | PLB1 isoform 2. | 0.772 |
| CHPT1 | PLD1 | ENSPTRP00000009103 | ENSPTRP00000042550 | Choline phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Phospholipase. | 0.940 |
| CHPT1 | PLD2 | ENSPTRP00000009103 | ENSPTRP00000014697 | Choline phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Phospholipase. | 0.940 |
| LCAT | APOA1 | ENSPTRP00000014085 | ENSPTRP00000007404 | Lecithin-cholesterol acyltransferase. | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility (By similarity). | 0.963 |
| LCAT | APOC1 | ENSPTRP00000014085 | ENSPTRP00000070626 | Lecithin-cholesterol acyltransferase. | Cholesteryl ester transfer inhibitor protein; Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor. Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL. Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP). Binds free fatty acids and reduces their intracellular esterification. [...] | 0.945 |
| LCAT | CEPT1 | ENSPTRP00000014085 | ENSPTRP00000092990 | Lecithin-cholesterol acyltransferase. | Choline/ethanolamine phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.914 |
| LCAT | CHPT1 | ENSPTRP00000014085 | ENSPTRP00000009103 | Lecithin-cholesterol acyltransferase. | Choline phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.923 |
