STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDH1CDH1 isoform 1; Cadherins are calcium-dependent cell adhesion proteins. (882 aa)    
Predicted Functional Partners:
CTNNB1
Catenin (Cadherin-associated protein), beta 1, 88kDa.
   
 0.999
CTNND1
CTNND1 isoform 23.
    
 0.999
JUP
Junction plakoglobin.
   
 0.998
CTNNA1
CTNNA1 isoform 21.
    
 0.997
KLRG1
Killer cell lectin like receptor G1.
    
 0.996
CTNNA2
CTNNA2 isoform 11.
    
 0.979
CTNNA3
CTNNA3 isoform 1.
    
 0.976
EGFR
Receptor protein-tyrosine kinase.
   
 
 0.969
PSEN1
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
 0.945
CBLL1
Cas-Br-M (Murine) ecotropic retroviral transforming sequence-like 1.
    
 
 0.945
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.