Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CHMP1A | CHMP4C | ENSPTRP00000014470 | ENSPTRP00000034862 | CHMP1A isoform 6. | Charged multivesicular body protein 4C. | 0.989 |
| CHMP1A | MLKL | ENSPTRP00000014470 | ENSPTRP00000014256 | CHMP1A isoform 6. | Mixed lineage kinase domain like pseudokinase. | 0.925 |
| CHMP4C | CHMP1A | ENSPTRP00000034862 | ENSPTRP00000014470 | Charged multivesicular body protein 4C. | CHMP1A isoform 6. | 0.989 |
| CHMP4C | MLKL | ENSPTRP00000034862 | ENSPTRP00000014256 | Charged multivesicular body protein 4C. | Mixed lineage kinase domain like pseudokinase. | 0.929 |
| HSP90AA1 | HSP90AB1 | ENSPTRP00000070946 | ENSPTRP00000031135 | Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...] | HSP90AB1 isoform 1. | 0.999 |
| HSP90AA1 | LOC107968084 | ENSPTRP00000070946 | ENSPTRP00000088532 | Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...] | Heat shock protein HSP 90-beta-like. | 0.979 |
| HSP90AA1 | MLKL | ENSPTRP00000070946 | ENSPTRP00000014256 | Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...] | Mixed lineage kinase domain like pseudokinase. | 0.944 |
| HSP90AA1 | NLRP3 | ENSPTRP00000070946 | ENSPTRP00000003728 | Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...] | NLRP3 isoform 2. | 0.920 |
| HSP90AA1 | RIPK3 | ENSPTRP00000070946 | ENSPTRP00000010556 | Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...] | Receptor interacting serine/threonine kinase 3. | 0.958 |
| HSP90AA1 | TNF | ENSPTRP00000070946 | ENSPTRP00000069905 | Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...] | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] | 0.465 |
| HSP90AB1 | HSP90AA1 | ENSPTRP00000031135 | ENSPTRP00000070946 | HSP90AB1 isoform 1. | Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...] | 0.999 |
| HSP90AB1 | LOC107968084 | ENSPTRP00000031135 | ENSPTRP00000088532 | HSP90AB1 isoform 1. | Heat shock protein HSP 90-beta-like. | 0.905 |
| HSP90AB1 | MLKL | ENSPTRP00000031135 | ENSPTRP00000014256 | HSP90AB1 isoform 1. | Mixed lineage kinase domain like pseudokinase. | 0.939 |
| HSP90AB1 | NLRP3 | ENSPTRP00000031135 | ENSPTRP00000003728 | HSP90AB1 isoform 1. | NLRP3 isoform 2. | 0.920 |
| HSP90AB1 | RIPK3 | ENSPTRP00000031135 | ENSPTRP00000010556 | HSP90AB1 isoform 1. | Receptor interacting serine/threonine kinase 3. | 0.954 |
| HSP90AB1 | TNF | ENSPTRP00000031135 | ENSPTRP00000069905 | HSP90AB1 isoform 1. | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] | 0.465 |
| LOC107968084 | HSP90AA1 | ENSPTRP00000088532 | ENSPTRP00000070946 | Heat shock protein HSP 90-beta-like. | Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...] | 0.979 |
| LOC107968084 | HSP90AB1 | ENSPTRP00000088532 | ENSPTRP00000031135 | Heat shock protein HSP 90-beta-like. | HSP90AB1 isoform 1. | 0.905 |
| LOC107968084 | MLKL | ENSPTRP00000088532 | ENSPTRP00000014256 | Heat shock protein HSP 90-beta-like. | Mixed lineage kinase domain like pseudokinase. | 0.925 |
| LOC107968084 | NLRP3 | ENSPTRP00000088532 | ENSPTRP00000003728 | Heat shock protein HSP 90-beta-like. | NLRP3 isoform 2. | 0.920 |
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