STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM92BFamily with sequence similarity 92 member B. (304 aa)    
Predicted Functional Partners:
SPINK6
Serine peptidase inhibitor, Kazal type 6.
      
 0.889
SPINK14
Serine peptidase inhibitor, Kazal type 14 (putative).
      
 0.888
SIX6
SIX homeobox 6.
      
 0.848
DSTYK
Dual serine/threonine and tyrosine protein kinase; Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. Involved in the regulation of both caspase-dependent apoptosis and caspase- independent cell death. In the skin, it plays a predominant role in suppressing caspase-dependent apoptosis in response to UV stress in a range of dermal cell types.
   
 0.844
LOC736783
Chymotrypsinogen B2.
      
 0.792
RHOH
RHOH isoform 10.
    
 0.790
IFITM2
Interferon induced transmembrane protein 2.
      
 0.685
CTRB2
Chymotrypsinogen B2.
      
 0.562
NCF4
Neutrophil cytosolic factor 4.
      
 0.502
PHOX2B
Paired like homeobox 2B.
   
  
 0.476
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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