ASPA protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADSS1	ADSS2	ENSPTRP00000011563	ENSPTRP00000003684	Adenylosuccinate synthetase isozyme 1 isoform X2.	ADSS isoform 1.	0.901
ADSS1	ASNS	ENSPTRP00000011563	ENSPTRP00000033236	Adenylosuccinate synthetase isozyme 1 isoform X2.	Asparagine synthetase [glutamine-hydrolyzing].	0.917
ADSS1	ASPA	ENSPTRP00000011563	ENSPTRP00000014620	Adenylosuccinate synthetase isozyme 1 isoform X2.	Aspartoacylase (Canavan disease).	0.900
ADSS1	ASRGL1	ENSPTRP00000011563	ENSPTRP00000006475	Adenylosuccinate synthetase isozyme 1 isoform X2.	Asparaginase like 1.	0.906
ADSS1	GOT1	ENSPTRP00000011563	ENSPTRP00000004968	Adenylosuccinate synthetase isozyme 1 isoform X2.	Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...]	0.919
ADSS1	GOT2	ENSPTRP00000011563	ENSPTRP00000013976	Adenylosuccinate synthetase isozyme 1 isoform X2.	Aspartate aminotransferase.	0.916
ADSS1	NAT8L	ENSPTRP00000011563	ENSPTRP00000062792	Adenylosuccinate synthetase isozyme 1 isoform X2.	NAT8L isoform 2.	0.900
ADSS2	ADSS1	ENSPTRP00000003684	ENSPTRP00000011563	ADSS isoform 1.	Adenylosuccinate synthetase isozyme 1 isoform X2.	0.901
ADSS2	ASNS	ENSPTRP00000003684	ENSPTRP00000033236	ADSS isoform 1.	Asparagine synthetase [glutamine-hydrolyzing].	0.917
ADSS2	ASPA	ENSPTRP00000003684	ENSPTRP00000014620	ADSS isoform 1.	Aspartoacylase (Canavan disease).	0.901
ADSS2	ASRGL1	ENSPTRP00000003684	ENSPTRP00000006475	ADSS isoform 1.	Asparaginase like 1.	0.909
ADSS2	GOT1	ENSPTRP00000003684	ENSPTRP00000004968	ADSS isoform 1.	Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...]	0.919
ADSS2	GOT2	ENSPTRP00000003684	ENSPTRP00000013976	ADSS isoform 1.	Aspartate aminotransferase.	0.930
ADSS2	NAT8L	ENSPTRP00000003684	ENSPTRP00000062792	ADSS isoform 1.	NAT8L isoform 2.	0.900
ASNS	ADSS1	ENSPTRP00000033236	ENSPTRP00000011563	Asparagine synthetase [glutamine-hydrolyzing].	Adenylosuccinate synthetase isozyme 1 isoform X2.	0.917
ASNS	ADSS2	ENSPTRP00000033236	ENSPTRP00000003684	Asparagine synthetase [glutamine-hydrolyzing].	ADSS isoform 1.	0.917
ASNS	ASPA	ENSPTRP00000033236	ENSPTRP00000014620	Asparagine synthetase [glutamine-hydrolyzing].	Aspartoacylase (Canavan disease).	0.910
ASNS	ASRGL1	ENSPTRP00000033236	ENSPTRP00000006475	Asparagine synthetase [glutamine-hydrolyzing].	Asparaginase like 1.	0.945
ASNS	GOT1	ENSPTRP00000033236	ENSPTRP00000004968	Asparagine synthetase [glutamine-hydrolyzing].	Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...]	0.951
ASNS	GOT2	ENSPTRP00000033236	ENSPTRP00000013976	Asparagine synthetase [glutamine-hydrolyzing].	Aspartate aminotransferase.	0.949