P2RX1 protein (Pan troglodytes) - STRING interaction network

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Score

P2RX1

P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)

Predicted Functional Partners:

P2RX3

0.980

P2RX7

0.950

CHRNA7

0.912

GRIN2C

0.907

GRIN2A

0.906

P2RX2

0.793

ITGAE

0.767

P2RX6

0.765

ENSPTRP00000074534

0.765

P2RY1

0.714

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHRNA7	GRIN2A	ENSPTRP00000011728	ENSPTRP00000055315	CHRNA7 isoform 7.	Glutamate receptor ionotropic, NMDA 2A; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition; channels containing GRIN1 and GRIN2A have higher sensitivity to glutamate and faster kineti [...]	0.923
CHRNA7	GRIN2C	ENSPTRP00000011728	ENSPTRP00000072438	CHRNA7 isoform 7.	GRIN2C isoform 4.	0.908
CHRNA7	P2RX1	ENSPTRP00000011728	ENSPTRP00000014652	CHRNA7 isoform 7.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.912
CHRNA7	P2RX3	ENSPTRP00000011728	ENSPTRP00000061714	CHRNA7 isoform 7.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.901
CHRNA7	P2RX7	ENSPTRP00000011728	ENSPTRP00000049853	CHRNA7 isoform 7.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	0.905
ENSPTRP00000074534	P2RX1	ENSPTRP00000074534	ENSPTRP00000014652	annotation not available	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.765
ENSPTRP00000074534	P2RX2	ENSPTRP00000074534	ENSPTRP00000082887	annotation not available	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	0.781
ENSPTRP00000074534	P2RX3	ENSPTRP00000074534	ENSPTRP00000061714	annotation not available	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.743
GRIN2A	CHRNA7	ENSPTRP00000055315	ENSPTRP00000011728	Glutamate receptor ionotropic, NMDA 2A; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition; channels containing GRIN1 and GRIN2A have higher sensitivity to glutamate and faster kineti [...]	CHRNA7 isoform 7.	0.923
GRIN2A	GRIN2C	ENSPTRP00000055315	ENSPTRP00000072438	Glutamate receptor ionotropic, NMDA 2A; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition; channels containing GRIN1 and GRIN2A have higher sensitivity to glutamate and faster kineti [...]	GRIN2C isoform 4.	0.997
GRIN2A	P2RX1	ENSPTRP00000055315	ENSPTRP00000014652	Glutamate receptor ionotropic, NMDA 2A; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition; channels containing GRIN1 and GRIN2A have higher sensitivity to glutamate and faster kineti [...]	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.906
GRIN2A	P2RX3	ENSPTRP00000055315	ENSPTRP00000061714	Glutamate receptor ionotropic, NMDA 2A; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition; channels containing GRIN1 and GRIN2A have higher sensitivity to glutamate and faster kineti [...]	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.906
GRIN2A	P2RX7	ENSPTRP00000055315	ENSPTRP00000049853	Glutamate receptor ionotropic, NMDA 2A; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition; channels containing GRIN1 and GRIN2A have higher sensitivity to glutamate and faster kineti [...]	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	0.900
GRIN2C	CHRNA7	ENSPTRP00000072438	ENSPTRP00000011728	GRIN2C isoform 4.	CHRNA7 isoform 7.	0.908
GRIN2C	GRIN2A	ENSPTRP00000072438	ENSPTRP00000055315	GRIN2C isoform 4.	Glutamate receptor ionotropic, NMDA 2A; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition; channels containing GRIN1 and GRIN2A have higher sensitivity to glutamate and faster kineti [...]	0.997
GRIN2C	P2RX1	ENSPTRP00000072438	ENSPTRP00000014652	GRIN2C isoform 4.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.907
GRIN2C	P2RX3	ENSPTRP00000072438	ENSPTRP00000061714	GRIN2C isoform 4.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.900
GRIN2C	P2RX7	ENSPTRP00000072438	ENSPTRP00000049853	GRIN2C isoform 4.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	0.900
ITGAE	P2RX1	ENSPTRP00000088066	ENSPTRP00000014652	ITGAE isoform 1; Belongs to the integrin alpha chain family.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.767
P2RX1	CHRNA7	ENSPTRP00000014652	ENSPTRP00000011728	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	CHRNA7 isoform 7.	0.912