STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM4SF5Transmembrane 4 L six family member 5. (197 aa)    
Predicted Functional Partners:
TSPAN1
Tetraspanin.
      
 0.626
CDHR1
Cadherin related family member 1.
   
  
 0.594
EGFR
Receptor protein-tyrosine kinase.
   
  
 0.574
TSPAN7
Tetraspanin-7; May be involved in cell proliferation and cell motility; Belongs to the tetraspanin (TM4SF) family.
      
 0.546
FABP1
Fatty acid binding protein 1.
   
    0.533
ITGA5
ITGA5 isoform 2; Belongs to the integrin alpha chain family.
   
  
 0.475
CD151
Tetraspanin.
      
 0.472
A1CF
A1CF isoform 9.
   
    0.439
AHSG
Alpha-2-HS-glycoprotein chain A; Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions (By similarity); Belongs to the fetuin family.
   
    0.407
ITGA2
Integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor); Belongs to the integrin alpha chain family.
   
  
 0.403
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.