STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GPS2G protein pathway suppressor 2. (327 aa)    
Predicted Functional Partners:
NCOR1
Nuclear receptor corepressor 1.
    
 0.988
NCOR2
Nuclear receptor corepressor 2.
    
 0.976
HDAC3
Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
    
 0.959
TBL1XR1
Transducin (Beta)-like 1 X-linked receptor 1.
   
 0.926
TBL1X
Transducin (Beta)-like 1X-linked.
   
 0.873
TBL1Y
TBL1X isoform 5.
   
 0.873
NR1D1
Nuclear receptor subfamily 1, group D, member 1.
    
 0.770
TAF12
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa.
    
 0.766
TADA3
Transcriptional adaptor 3.
    
 0.756
TAF10
Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.
    
 0.745
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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