STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RANGRFRAN guanine nucleotide release factor. (186 aa)    
Predicted Functional Partners:
RAN
GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.
    
 
 0.806
ENSPTRP00000079197
annotation not available
    
 
 0.779
RANBP1
RAN binding protein 1.
    
 
 0.750
ADGRD1
ADGRD1 isoform 6; Belongs to the G-protein coupled receptor 2 family.
    
 
 0.748
RANBP1-2
RANBP1 isoform 4.
    
 
 0.678
SCN5A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
      
 0.661
ADGRB3
Adhesion G protein-coupled receptor B3; Belongs to the G-protein coupled receptor 2 family.
    
 
 0.611
ADGRB2
Adhesion G protein-coupled receptor B2; Belongs to the G-protein coupled receptor 2 family.
    
 
 0.611
ADGRB1
Adhesion G protein-coupled receptor B1; Belongs to the G-protein coupled receptor 2 family.
    
 
 0.611
GPD1L
Glycerol-3-phosphate dehydrogenase [NAD(+)].
      
 0.583
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.