STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRPSAP2Phosphoribosyl pyrophosphate synthetase-associated protein 2. (369 aa)    
Predicted Functional Partners:
ENSPTRP00000062095
annotation not available
  
0.831
PRPS1
Phosphoribosyl pyrophosphate synthetase 1.
  
0.827
PRPS2
Phosphoribosyl pyrophosphate synthetase 2.
  
0.827
PDHB
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
   
 0.742
BCKDHB
BCKDHB isoform 1.
   
 0.742
KARS1
KARS isoform 4.
   
 
 0.688
EPRS1
EPRS isoform 1.
  
 
 0.658
DBT
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
   
 0.591
DLAT
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
   
 0.591
DLST
Dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex).
   
 0.591
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.