STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa)    
Predicted Functional Partners:
LEF1
Lymphoid enhancer binding factor 1.
    
 0.992
MAP3K7
Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
    
0.982
TCF7
Transcription factor 7.
    
 0.977
FOXO1
FOXO1 isoform 1.
    
 0.934
FOXO3
FOXO3 isoform 1.
    
 0.914
FOXO6
FOXO6 isoform 2.
    
 0.911
TCF7L2
Transcription factor 7 like 2.
    
 0.858
CTNNB1
Catenin (Cadherin-associated protein), beta 1, 88kDa.
    
 0.814
TCF7L1
Transcription factor 7 like 1.
    
 0.793
MAP3K20
Sterile alpha motif and leucine zipper containing kinase AZK.
    
0.782
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.