STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VTNVTN isoform 1. (478 aa)    
Predicted Functional Partners:
SERPINE1
Serpin family E member 1; Belongs to the serpin family.
   
 0.997
ITGAV
Integrin, alpha V (Vitronectin receptor, alpha polypeptide, antigen CD51); Belongs to the integrin alpha chain family.
   
 0.982
ITGB3
Integrin beta-3 isoform X2.
    
 0.982
ITGB5
Integrin beta; Belongs to the integrin beta chain family.
    
 0.981
ITGA8
Integrin subunit alpha 8; Belongs to the integrin alpha chain family.
   
 0.976
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
    
 0.975
PLAUR
Urokinase plasminogen activator surface receptor; Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form (By similarity).
    
 0.973
ITGB8
Integrin beta; Belongs to the integrin beta chain family.
    
 0.959
ITGA5
ITGA5 isoform 2; Belongs to the integrin alpha chain family.
   
 0.909
PLAU
Plasminogen activator, urokinase.
   
 0.877
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.