SUPT6H protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTDP1	EAF1	ENSPTRP00000017217	ENSPTRP00000025292	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	ELL associated factor 1.	0.934
CTDP1	ENSPTRP00000061528	ENSPTRP00000017217	ENSPTRP00000061528	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	annotation not available	0.603
CTDP1	IWS1	ENSPTRP00000017217	ENSPTRP00000021285	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	Interacts with SUPT6H, CTD assembly factor 1.	0.941
CTDP1	POLR2A	ENSPTRP00000017217	ENSPTRP00000042468	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.982
CTDP1	SSRP1	ENSPTRP00000017217	ENSPTRP00000006311	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.685
CTDP1	SUPT16H	ENSPTRP00000017217	ENSPTRP00000010390	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	SPT16 homolog, facilitates chromatin remodeling subunit.	0.603
CTDP1	SUPT4H1	ENSPTRP00000017217	ENSPTRP00000016051	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.	0.889
CTDP1	SUPT5H	ENSPTRP00000017217	ENSPTRP00000082786	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	Transcription elongation factor SPT5.	0.865
CTDP1	SUPT6H	ENSPTRP00000017217	ENSPTRP00000015242	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family.	0.954
CTDP1	TCEA1	ENSPTRP00000017217	ENSPTRP00000075657	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	Transcription elongation factor A (SII), 1.	0.890
EAF1	CTDP1	ENSPTRP00000025292	ENSPTRP00000017217	ELL associated factor 1.	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	0.934
EAF1	IWS1	ENSPTRP00000025292	ENSPTRP00000021285	ELL associated factor 1.	Interacts with SUPT6H, CTD assembly factor 1.	0.933
EAF1	POLR2A	ENSPTRP00000025292	ENSPTRP00000042468	ELL associated factor 1.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.558
EAF1	SSRP1	ENSPTRP00000025292	ENSPTRP00000006311	ELL associated factor 1.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.552
EAF1	SUPT4H1	ENSPTRP00000025292	ENSPTRP00000016051	ELL associated factor 1.	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.	0.897
EAF1	SUPT5H	ENSPTRP00000025292	ENSPTRP00000082786	ELL associated factor 1.	Transcription elongation factor SPT5.	0.828
EAF1	SUPT6H	ENSPTRP00000025292	ENSPTRP00000015242	ELL associated factor 1.	Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family.	0.931
EAF1	TCEA1	ENSPTRP00000025292	ENSPTRP00000075657	ELL associated factor 1.	Transcription elongation factor A (SII), 1.	0.880
ENSPTRP00000061528	CTDP1	ENSPTRP00000061528	ENSPTRP00000017217	annotation not available	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	0.603
ENSPTRP00000061528	IWS1	ENSPTRP00000061528	ENSPTRP00000021285	annotation not available	Interacts with SUPT6H, CTD assembly factor 1.	0.868