STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEZ6Seizure related 6 homolog. (994 aa)    
Predicted Functional Partners:
SKAP1
Src kinase associated phosphoprotein 1.
      
 0.742
CD6
CD6 isoform 1.
    
 0.688
LHX3
LHX3 isoform 2.
   
  
 0.560
IRF2
Interferon regulatory factor.
    
 0.486
MPDZ
Multiple PDZ domain crumbs cell polarity complex component.
    
 0.442
AP2M1
AP2M1 isoform 3; Belongs to the adaptor complexes medium subunit family.
    
  0.402
GAK
Cyclin G associated kinase.
    
 0.401
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.