STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NF1Neurofibromin 1. (2839 aa)    
Predicted Functional Partners:
NRAS
Neuroblastoma RAS viral (V-ras) oncogene homolog.
   
 0.991
KRAS
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.
   
 0.990
HRAS
V-Ha-ras Harvey rat sarcoma viral oncogene homolog.
   
 0.986
SPRED1
Sprouty-related, EVH1 domain containing 1.
    
 0.965
RRAS
Related RAS viral (R-ras) oncogene homolog.
   
 0.958
RRAS2
Related RAS viral (R-ras) oncogene homolog 2.
   
 0.954
MRAS
Muscle RAS oncogene homolog.
   
 0.954
SPRED2
SPRED2 isoform 3.
    
 0.878
SLC6A18
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
   
 
 0.822
NF2
Neurofibromin 2 (Merlin).
      
 0.802
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.