STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SYNRGSYNRG isoform 1. (1338 aa)    
Predicted Functional Partners:
ITSN2
ITSN2 isoform 1.
   
 0.978
AP1G2
AP-1 complex subunit gamma.
   
 0.940
AP1G1
AP-1 complex subunit gamma.
   
 0.927
AFTPH
AFTPH isoform 1.
   
 0.899
ITSN1
ITSN1 isoform 4.
   
 0.855
ITSN1-2
ITSN1 isoform 7.
   
 0.855
AP2A1
AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]
   
 0.823
GAK
Cyclin G associated kinase.
   
 0.803
AP1S2
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.802
AP2M1
AP2M1 isoform 3; Belongs to the adaptor complexes medium subunit family.
    
 0.789
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.