| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCNA1 | CCNA2 | ENSPTRP00000070605 | ENSPTRP00000028181 | CCNA1 isoform 3; Belongs to the cyclin family. | CCNA2 isoform 1; Belongs to the cyclin family. | 0.994 |
| CCNA1 | CDC6 | ENSPTRP00000070605 | ENSPTRP00000015543 | CCNA1 isoform 3; Belongs to the cyclin family. | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | 0.997 |
| CCNA1 | CDK2 | ENSPTRP00000070605 | ENSPTRP00000067097 | CCNA1 isoform 3; Belongs to the cyclin family. | CDK2 isoform 4; Belongs to the protein kinase superfamily. | 0.999 |
| CCNA1 | CDT1 | ENSPTRP00000070605 | ENSPTRP00000014432 | CCNA1 isoform 3; Belongs to the cyclin family. | Chromatin licensing and DNA replication factor 1. | 0.964 |
| CCNA1 | MCM10 | ENSPTRP00000070605 | ENSPTRP00000044662 | CCNA1 isoform 3; Belongs to the cyclin family. | Minichromosome maintenance complex component 10. | 0.742 |
| CCNA1 | MCM3 | ENSPTRP00000070605 | ENSPTRP00000031227 | CCNA1 isoform 3; Belongs to the cyclin family. | DNA helicase; Belongs to the MCM family. | 0.824 |
| CCNA1 | MCM7 | ENSPTRP00000070605 | ENSPTRP00000033323 | CCNA1 isoform 3; Belongs to the cyclin family. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.876 |
| CCNA1 | ORC1 | ENSPTRP00000070605 | ENSPTRP00000001270 | CCNA1 isoform 3; Belongs to the cyclin family. | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.936 |
| CCNA1 | ORC4 | ENSPTRP00000070605 | ENSPTRP00000021407 | CCNA1 isoform 3; Belongs to the cyclin family. | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. | 0.640 |
| CCNA1 | ORC6 | ENSPTRP00000070605 | ENSPTRP00000013796 | CCNA1 isoform 3; Belongs to the cyclin family. | Origin recognition complex, subunit 6. | 0.676 |
| CCNA2 | CCNA1 | ENSPTRP00000028181 | ENSPTRP00000070605 | CCNA2 isoform 1; Belongs to the cyclin family. | CCNA1 isoform 3; Belongs to the cyclin family. | 0.994 |
| CCNA2 | CDC6 | ENSPTRP00000028181 | ENSPTRP00000015543 | CCNA2 isoform 1; Belongs to the cyclin family. | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | 0.998 |
| CCNA2 | CDK2 | ENSPTRP00000028181 | ENSPTRP00000067097 | CCNA2 isoform 1; Belongs to the cyclin family. | CDK2 isoform 4; Belongs to the protein kinase superfamily. | 0.999 |
| CCNA2 | CDT1 | ENSPTRP00000028181 | ENSPTRP00000014432 | CCNA2 isoform 1; Belongs to the cyclin family. | Chromatin licensing and DNA replication factor 1. | 0.988 |
| CCNA2 | MCM10 | ENSPTRP00000028181 | ENSPTRP00000044662 | CCNA2 isoform 1; Belongs to the cyclin family. | Minichromosome maintenance complex component 10. | 0.766 |
| CCNA2 | MCM3 | ENSPTRP00000028181 | ENSPTRP00000031227 | CCNA2 isoform 1; Belongs to the cyclin family. | DNA helicase; Belongs to the MCM family. | 0.822 |
| CCNA2 | MCM7 | ENSPTRP00000028181 | ENSPTRP00000033323 | CCNA2 isoform 1; Belongs to the cyclin family. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.878 |
| CCNA2 | ORC1 | ENSPTRP00000028181 | ENSPTRP00000001270 | CCNA2 isoform 1; Belongs to the cyclin family. | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.970 |
| CCNA2 | ORC4 | ENSPTRP00000028181 | ENSPTRP00000021407 | CCNA2 isoform 1; Belongs to the cyclin family. | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. | 0.609 |
| CCNA2 | ORC6 | ENSPTRP00000028181 | ENSPTRP00000013796 | CCNA2 isoform 1; Belongs to the cyclin family. | Origin recognition complex, subunit 6. | 0.644 |
