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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRT25Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization (By similarity). (450 aa)    
Predicted Functional Partners:
KRT71
KRT71 isoform 1; Belongs to the intermediate filament family.
  
0.849
KRT27
KRT27 isoform 1; Belongs to the intermediate filament family.
  
0.842
KRTAP3-3
KRTAP3-3 isoform 1.
  
 
 0.681
UNC79
UNC79 isoform 1.
   
 0.680
KRT83
Keratin, type II cuticular Hb3.
  
0.604
LOC745232
KRTAP3-2 isoform 1.
  
 
 0.581
TCHH
TCHH isoform 1.
   
 0.500
KRT74
KRT74 isoform 2; Belongs to the intermediate filament family.
  
 
0.479
KRT35
KRT35 isoform 1; Belongs to the intermediate filament family.
  
 
 
0.452
GSDMA
GSDMA isoform 1.
  
   
 0.442
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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