STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRT12KRT12 isoform 1; Belongs to the intermediate filament family. (494 aa)    
Predicted Functional Partners:
UNC79
UNC79 isoform 1.
   
 0.680
PAX6
PAX6 isoform 13.
      
 0.591
KERA
KERA isoform 1.
    
 0.525
CRYZ
Crystallin, zeta (Quinone reductase).
    
 
 0.467
GRIK1
Glutamate ionotropic receptor kainate type subunit 1.
   
  
 0.465
FSHB
Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs.
      
 0.463
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2.
   
 
 0.462
CHST6
Sulfotransferase; Belongs to the sulfotransferase 1 family.
     
 0.461
ALDH3A1
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 
 0.439
KDM6B
Lysine demethylase 6B.
   
 0.433
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.