STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRT36KRT36 isoform 2; Belongs to the intermediate filament family. (467 aa)    
Predicted Functional Partners:
UNC79
UNC79 isoform 1.
    
 0.675
CSF3R
CSF3R isoform 3.
   
 0.472
MAL
Mal, T cell differentiation protein.
  
   
 0.456
KRT84
KRT84 isoform 1; Belongs to the intermediate filament family.
  
 
0.454
KDM6B
Lysine demethylase 6B.
    
 0.425
KDM6A
KDM6A isoform 1.
    
 0.425
UTY
Histone demethylase UTY; Male-specific histone demethylase that catalyzes trimethylated 'Lys-27' (H3K27me3) demethylation in histone H3. Has relatively low lysine demethylase activity.
    
 0.425
ASH2L
ASH2 like, histone lysine methyltransferase complex subunit.
    
 0.416
RBBP5
RB binding protein 5, histone lysine methyltransferase complex subunit.
    
 0.414
RANBP2-2
E3 SUMO-protein ligase RanBP2; E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I. Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via the F-G repeat-containing domain which acts as a docking site for substrates. Component of the nuclear export pathway. Specific docking site for the nuclear export factor exportin-1. Sumoylates PML at 'Lys-490' which is essential for the proper assembly of PML-NB. Recruits BICD2 to the nuclear envelope and cytoplasmic stacks of nuclear pore complex known as annulate lamellae during G2 phase of cell [...]
    
 0.412
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.