STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JUPJunction plakoglobin. (745 aa)    
Predicted Functional Partners:
CDH1
CDH1 isoform 1; Cadherins are calcium-dependent cell adhesion proteins.
   
 0.998
DSP
DSP isoform 1.
   
 0.992
CTNNB1
Catenin (Cadherin-associated protein), beta 1, 88kDa.
  
 
0.992
CCDC130
Coiled-coil domain containing 130.
   
   0.984
LEF1
Lymphoid enhancer binding factor 1.
    
 0.979
TCF7
Transcription factor 7.
    
 0.977
DSG2
DSG2 isoform 1.
    
 0.964
CTNNA1
CTNNA1 isoform 21.
   
 0.962
APC
Adenomatous polyposis coli protein isoform X10.
   
 0.957
PKP2
PKP2 isoform 1.
   
 0.945
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.