NAGS protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASL	ENSPTRP00000071311	ENSPTRP00000056449	ENSPTRP00000071311	Argininosuccinate lyase.	annotation not available	0.884
ASL	NAGS	ENSPTRP00000056449	ENSPTRP00000015750	Argininosuccinate lyase.	N-acetylglutamate synthase.	0.976
ASL	OAT	ENSPTRP00000056449	ENSPTRP00000005344	Argininosuccinate lyase.	Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.884
ASL-2	ENSPTRP00000071311	ENSPTRP00000073709	ENSPTRP00000071311	Argininosuccinate lyase.	annotation not available	0.884
ASL-2	NAGS	ENSPTRP00000073709	ENSPTRP00000015750	Argininosuccinate lyase.	N-acetylglutamate synthase.	0.976
ASL-2	OAT	ENSPTRP00000073709	ENSPTRP00000005344	Argininosuccinate lyase.	Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.884
ENSPTRP00000071311	ASL	ENSPTRP00000071311	ENSPTRP00000056449	annotation not available	Argininosuccinate lyase.	0.884
ENSPTRP00000071311	ASL-2	ENSPTRP00000071311	ENSPTRP00000073709	annotation not available	Argininosuccinate lyase.	0.884
ENSPTRP00000071311	GLUD1	ENSPTRP00000071311	ENSPTRP00000004734	annotation not available	Glutamate dehydrogenase 2, mitochondrial; Important for recycling the chief excitatory neurotransmitter, glutamate, during neurotransmission; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.627
ENSPTRP00000071311	NAGS	ENSPTRP00000071311	ENSPTRP00000015750	annotation not available	N-acetylglutamate synthase.	0.953
GLUD1	ENSPTRP00000071311	ENSPTRP00000004734	ENSPTRP00000071311	Glutamate dehydrogenase 2, mitochondrial; Important for recycling the chief excitatory neurotransmitter, glutamate, during neurotransmission; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	annotation not available	0.627
GLUD1	GOT1	ENSPTRP00000004734	ENSPTRP00000004968	Glutamate dehydrogenase 2, mitochondrial; Important for recycling the chief excitatory neurotransmitter, glutamate, during neurotransmission; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...]	0.954
GLUD1	GOT1L1	ENSPTRP00000004734	ENSPTRP00000093290	Glutamate dehydrogenase 2, mitochondrial; Important for recycling the chief excitatory neurotransmitter, glutamate, during neurotransmission; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	GOT1L1 isoform 1.	0.944
GLUD1	GOT2	ENSPTRP00000004734	ENSPTRP00000013976	Glutamate dehydrogenase 2, mitochondrial; Important for recycling the chief excitatory neurotransmitter, glutamate, during neurotransmission; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Aspartate aminotransferase.	0.948
GLUD1	GPT	ENSPTRP00000004734	ENSPTRP00000039118	Glutamate dehydrogenase 2, mitochondrial; Important for recycling the chief excitatory neurotransmitter, glutamate, during neurotransmission; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Glutamic--pyruvic transaminase.	0.940
GLUD1	GPT2	ENSPTRP00000004734	ENSPTRP00000013801	Glutamate dehydrogenase 2, mitochondrial; Important for recycling the chief excitatory neurotransmitter, glutamate, during neurotransmission; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Glutamic pyruvate transaminase (Alanine aminotransferase) 2.	0.940
GLUD1	NAGS	ENSPTRP00000004734	ENSPTRP00000015750	Glutamate dehydrogenase 2, mitochondrial; Important for recycling the chief excitatory neurotransmitter, glutamate, during neurotransmission; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	N-acetylglutamate synthase.	0.921
GLUD1	OAT	ENSPTRP00000004734	ENSPTRP00000005344	Glutamate dehydrogenase 2, mitochondrial; Important for recycling the chief excitatory neurotransmitter, glutamate, during neurotransmission; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.627
GOT1	GLUD1	ENSPTRP00000004968	ENSPTRP00000004734	Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...]	Glutamate dehydrogenase 2, mitochondrial; Important for recycling the chief excitatory neurotransmitter, glutamate, during neurotransmission; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.954
GOT1	GOT1L1	ENSPTRP00000004968	ENSPTRP00000093290	Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...]	GOT1L1 isoform 1.	0.922