| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EME1 | EME2 | ENSPTRP00000015960 | ENSPTRP00000061043 | Essential meiotic structure-specific endonuclease 1. | Essential meiotic structure-specific endonuclease subunit 2. | 0.947 |
| EME1 | ERCC1 | ENSPTRP00000015960 | ENSPTRP00000076815 | Essential meiotic structure-specific endonuclease 1. | ERCC excision repair 1, endonuclease non-catalytic subunit. | 0.903 |
| EME1 | ERCC4 | ENSPTRP00000015960 | ENSPTRP00000053757 | Essential meiotic structure-specific endonuclease 1. | Excision repair cross-complementing rodent repair deficiency, complementation group 4. | 0.884 |
| EME1 | EXO1 | ENSPTRP00000015960 | ENSPTRP00000003664 | Essential meiotic structure-specific endonuclease 1. | EXO1 isoform 1. | 0.880 |
| EME1 | FANCI | ENSPTRP00000015960 | ENSPTRP00000012702 | Essential meiotic structure-specific endonuclease 1. | FANCI isoform 2. | 0.877 |
| EME1 | MUS81 | ENSPTRP00000015960 | ENSPTRP00000006717 | Essential meiotic structure-specific endonuclease 1. | MUS81 structure-specific endonuclease subunit. | 0.999 |
| EME1 | RAD51 | ENSPTRP00000015960 | ENSPTRP00000068995 | Essential meiotic structure-specific endonuclease 1. | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] | 0.875 |
| EME1 | RMI2 | ENSPTRP00000015960 | ENSPTRP00000013261 | Essential meiotic structure-specific endonuclease 1. | Chromosome 16 open reading frame 75. | 0.894 |
| EME1 | SLX1A | ENSPTRP00000015960 | ENSPTRP00000058845 | Essential meiotic structure-specific endonuclease 1. | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. | 0.965 |
| EME1 | SLX4 | ENSPTRP00000015960 | ENSPTRP00000013163 | Essential meiotic structure-specific endonuclease 1. | SLX4 structure-specific endonuclease subunit. | 0.993 |
| EME2 | EME1 | ENSPTRP00000061043 | ENSPTRP00000015960 | Essential meiotic structure-specific endonuclease subunit 2. | Essential meiotic structure-specific endonuclease 1. | 0.947 |
| EME2 | ERCC1 | ENSPTRP00000061043 | ENSPTRP00000076815 | Essential meiotic structure-specific endonuclease subunit 2. | ERCC excision repair 1, endonuclease non-catalytic subunit. | 0.551 |
| EME2 | ERCC4 | ENSPTRP00000061043 | ENSPTRP00000053757 | Essential meiotic structure-specific endonuclease subunit 2. | Excision repair cross-complementing rodent repair deficiency, complementation group 4. | 0.777 |
| EME2 | EXO1 | ENSPTRP00000061043 | ENSPTRP00000003664 | Essential meiotic structure-specific endonuclease subunit 2. | EXO1 isoform 1. | 0.723 |
| EME2 | FANCI | ENSPTRP00000061043 | ENSPTRP00000012702 | Essential meiotic structure-specific endonuclease subunit 2. | FANCI isoform 2. | 0.478 |
| EME2 | MUS81 | ENSPTRP00000061043 | ENSPTRP00000006717 | Essential meiotic structure-specific endonuclease subunit 2. | MUS81 structure-specific endonuclease subunit. | 0.999 |
| EME2 | RAD51 | ENSPTRP00000061043 | ENSPTRP00000068995 | Essential meiotic structure-specific endonuclease subunit 2. | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] | 0.706 |
| EME2 | RMI2 | ENSPTRP00000061043 | ENSPTRP00000013261 | Essential meiotic structure-specific endonuclease subunit 2. | Chromosome 16 open reading frame 75. | 0.639 |
| EME2 | SLX1A | ENSPTRP00000061043 | ENSPTRP00000058845 | Essential meiotic structure-specific endonuclease subunit 2. | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. | 0.565 |
| EME2 | SLX4 | ENSPTRP00000061043 | ENSPTRP00000013163 | Essential meiotic structure-specific endonuclease subunit 2. | SLX4 structure-specific endonuclease subunit. | 0.775 |
