STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AXIN2AXIN2 isoform 1. (843 aa)    
Predicted Functional Partners:
CTNNB1
Catenin (Cadherin-associated protein), beta 1, 88kDa.
   
 0.997
APC
Adenomatous polyposis coli protein isoform X10.
   
 0.995
CSNK1A1
Casein kinase 1, alpha 1; Belongs to the protein kinase superfamily.
    
 0.992
GSK3B
Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.
   
 0.987
APC2
APC2 isoform 1.
   
 0.982
LEF1
Lymphoid enhancer binding factor 1.
   
 0.981
DVL2
Dishevelled segment polarity protein 2.
   
0.977
DVL3
Dishevelled segment polarity protein 3.
   
0.976
TCF7
Transcription factor 7.
   
 0.972
CSNK1A1L
Casein kinase 1 alpha 1 like; Belongs to the protein kinase superfamily.
    
 0.965
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.