| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| COL2A1 | RUNX2 | ENSPTRP00000041995 | ENSPTRP00000065999 | Collagen type II alpha 1 chain. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.670 |
| COL2A1 | SOX9 | ENSPTRP00000041995 | ENSPTRP00000016293 | Collagen type II alpha 1 chain. | Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. | 0.829 |
| EP300 | GATA4 | ENSPTRP00000024841 | ENSPTRP00000075865 | E1A binding protein p300. | GATA binding protein 4. | 0.781 |
| EP300 | PRKACB | ENSPTRP00000024841 | ENSPTRP00000042330 | E1A binding protein p300. | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. | 0.929 |
| EP300 | PRKACG | ENSPTRP00000024841 | ENSPTRP00000035898 | E1A binding protein p300. | Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. | 0.929 |
| EP300 | RUNX2 | ENSPTRP00000024841 | ENSPTRP00000065999 | E1A binding protein p300. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.939 |
| EP300 | SOX8 | ENSPTRP00000024841 | ENSPTRP00000012939 | E1A binding protein p300. | SOX8 isoform 1. | 0.559 |
| EP300 | SOX9 | ENSPTRP00000024841 | ENSPTRP00000016293 | E1A binding protein p300. | Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. | 0.820 |
| FBXW7 | SOX9 | ENSPTRP00000028353 | ENSPTRP00000016293 | F-box and WD repeat domain containing 7. | Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. | 0.830 |
| GATA4 | EP300 | ENSPTRP00000075865 | ENSPTRP00000024841 | GATA binding protein 4. | E1A binding protein p300. | 0.781 |
| GATA4 | NR5A1 | ENSPTRP00000075865 | ENSPTRP00000036496 | GATA binding protein 4. | Nuclear receptor subfamily 5 group A member 1. | 0.818 |
| GATA4 | RUNX2 | ENSPTRP00000075865 | ENSPTRP00000065999 | GATA binding protein 4. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.561 |
| GATA4 | SOX8 | ENSPTRP00000075865 | ENSPTRP00000012939 | GATA binding protein 4. | SOX8 isoform 1. | 0.481 |
| GATA4 | SOX9 | ENSPTRP00000075865 | ENSPTRP00000016293 | GATA binding protein 4. | Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. | 0.873 |
| NR5A1 | GATA4 | ENSPTRP00000036496 | ENSPTRP00000075865 | Nuclear receptor subfamily 5 group A member 1. | GATA binding protein 4. | 0.818 |
| NR5A1 | PRKACB | ENSPTRP00000036496 | ENSPTRP00000042330 | Nuclear receptor subfamily 5 group A member 1. | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. | 0.912 |
| NR5A1 | PRKACG | ENSPTRP00000036496 | ENSPTRP00000035898 | Nuclear receptor subfamily 5 group A member 1. | Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. | 0.912 |
| NR5A1 | SOX8 | ENSPTRP00000036496 | ENSPTRP00000012939 | Nuclear receptor subfamily 5 group A member 1. | SOX8 isoform 1. | 0.563 |
| NR5A1 | SOX9 | ENSPTRP00000036496 | ENSPTRP00000016293 | Nuclear receptor subfamily 5 group A member 1. | Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. | 0.950 |
| PAX3 | SOX8 | ENSPTRP00000090733 | ENSPTRP00000012939 | PAX3 isoform 4. | SOX8 isoform 1. | 0.663 |
