STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AANATSerotonin N-acetyltransferase; Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N- acetylserotonin, the penultimate step in the synthesis of melatonin (By similarity); Belongs to the acetyltransferase family. AANAT subfamily. (207 aa)    
Predicted Functional Partners:
DDC
Dopa decarboxylase.
     
 0.960
IDO2
IDO2 isoform 4.
     
 0.940
MAOA
Amine oxidase.
     
 0.937
IDO1
IDO1 isoform 2.
     
 0.930
MAOB
Amine oxidase.
     
 0.918
INMT
INMT-MINDY4 isoform 2.
     
 0.900
ASMT
Acetylserotonin O-methyltransferase.
   
  
 0.845
YWHAZ
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide; Belongs to the 14-3-3 family.
    
 
 0.765
LOC100611246
14-3-3 protein zeta/delta pseudogene.
    
 
 0.765
OPN4
OPN4 isoform 3.
   
  
 0.679
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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